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Mouse Collagen Type II Alpha 1(COL2a1)ELISA Kit

TOPEL21256L
2-8℃
6个月
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TOPEL21256L 48T $247.68
TOPEL21256L 96T $316.48
Product Name Mouse Collagen Type II Alpha 1(COL2a1)ELISA Kit
Introduction： Ⅱ型胶原α1(COL2a1)是一个 II 型胶原蛋白的α-1 链，II 型胶原蛋白是一种纤 维状的胶原蛋白，存在于软骨和眼睛的玻璃体中。该基因的突变与软骨发育 不全、早发性家族性骨关节炎、先天性 SED、Langer-Saldino 软骨发育不全、 Kniest 发育不全、Stickler 综合征 I 型和 Strudwick 型脊柱骨骺线发育不全 有关。此外，加工软骨素的缺陷也与软骨发育不良有关，软骨素是一种钙结 合蛋白，是这种胶原分子的 C 肽。II 型胶原蛋白可增加结缔组织的结构和强 度，主要存在于软骨、填充眼球的果冻状物质（玻璃体）、内耳以及脊柱中 椎体之间的椎间盘中心部分（髓核）。三个 pro-alpha1(II)链缠绕在一起， 形成一个三股的、像绳索的 procollagen 分子。这些原胶原蛋白分子必须由 细胞内的酶来处理。一旦这些分子被处理，它们就会离开细胞并排列成长而 细的纤维状，在细胞周围的空间中相互交联。交联的结果是形成非常强大的 成熟 II 型胶原蛋白纤维

These protocols are for reference only. Biotopped does not independently validate these methods.

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