一种有效的选择性的ferroptosis抑制剂,EC50:60 nM。Ferrostatin-1 is a potent inhibitor of non-apoptotic cell death induced by erastin call ferroptosis. Ferrostatin-1 prevents ferroptopic cell death in cancer cells and glutamate-induced toxicity in organotypic rat brain slices. It appears that Ferrostatin-1 controls lipid soluble ROS.
These protocols are for reference only. Biotopped does not independently validate these methods.