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Mouse Growth Hormone Receptor(GHR)ELISA Kit

TOPEL15751L
2-8℃
6个月
Catalog No. Specification List Price Preferential Price VIP Beijing Harbin Quantity Cart
TOPEL15751L 48T $247.68
TOPEL15751L 96T $316.48
Product Name Mouse Growth Hormone Receptor(GHR)ELISA Kit
Introduction: 生长激素受体是一种蛋白质,由GHR基因编码。在大多数哺乳动物中都发现了GHR的同源物。该基因编码的蛋白质是生长激素的跨膜受体。生长激素与受体结合导致预组装的受体二聚体的重新定向(然而受体也可能在细胞表面以单体形式存在),并激活细胞内和细胞间的信号转导途径,导致生长。生长激素受体(GHR)是由620个氨基酸组成的跨膜蛋白。GHR以两种形式存在,一种是全长的膜结合受体,另一种是可溶性的GH结合蛋白(GHBP)。它在其胞外结构域中含有两个纤维蛋白III型β结构域,而胞内结构域含有酪氨酸激酶JAK2与SH2蛋白的结合点。JAK2是生长激素的主要信号转导者。

These protocols are for reference only. Biotopped does not independently validate these methods.

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