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Rat Trefoil Factor 1(TFF1)ELISA Kit

TOPEL30891L
2-8℃
6个月
Bulk Inquiry? Manual Download Collection Product
Catalog No. Specification List Price Preferential Price VIP Beijing Harbin Quantity Cart
TOPEL30891L 48T $288.96
TOPEL30891L 96T $440.32
Product Name Rat Trefoil Factor 1(TFF1)ELISA Kit
Introduction： 三叶因子1，也被称为TFF1，三叶因子1是一种蛋白质，由TFF1基因（也称为PS2基因）编码。它是三叶草家族的成员，这个家族成员的特征是至少有一个三叶草基序的副本，这是一个包含三个保守二硫化的40氨基酸结构域。它们是在胃肠粘膜中表达的稳定分泌蛋白。它们的功能尚未定义，但它们可以保护粘膜免受侮辱，稳定粘液层并影响上皮的愈合。该基因和另外两个相关的三叶草家族成员基因在21号染色体上的一个簇中被发现。它的表达在胃癌中经常丢失，可能是通过DNA甲基化的机制，因此被认为是肿瘤抑制基因。它主要在胃粘膜的中央凹上皮表面细胞中表达，并在炎症期间表现出增加表达的模式。它和其他TFF家族成员因炎症和胃肠道损伤而以自分泌和/或旁分泌方式上调和分泌。它激活的信号通路尚未完全阐明，主要是由于缺乏识别功能受体的数据。

These protocols are for reference only. Biotopped does not independently validate these methods.

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